Some people, when faced with uncertainty, weigh all the factual and interpretive possibilities and respond to the one that seems most probable. Sometimes they’ll cycle through a whole series of possibilities, one at a time.
Others generate multiple possibilities, and weigh the degree of uncertainty of each, looking for overlap between the most plausible possibilities. They then respond practically to the whole probabilistic cloud as a single situation.
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The latter approach is optimal for hermeneutics, for concepting, for psychology, and for pretty much any situation involving extreme indeterminacy or doubt. There’s the facts and there’s the interpretive arrangements, and each modifies the other. Knowing how to dismantle an interpretation (which can look for all the world like reality itself) into bits of data and then to reassemble them into multiple divergent interpretations, when combined with an active imagination and a nuanced recall results in the capacity to generate a vast array of persuasive possibilities. Everything is left liquid to some degree. It’s a gift and a curse.
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For a skeptic, no knowledge is complete until it includes the meta-knowledge of ground of certainty. To lose track of this is to lose command of the knowledge.